This study reports on the measurement invariance of the Agency of University Students Scale in data consisting of Finnish and Spanish university students (n = 645) and presents cross-national findings on student agency assessment. Multigroup confirmatory factor analysis confirmed the metric invariance for 10 factors, which allows comparisons of covariance structures and correlation analyses, and can, for example, be used to examine background factor effects on agency across groups. At least partial scalar invariance was confirmed for six factors, allowing comparisons of mean values between Finnish and Spanish students. Differences were found in the experiences of personal and relational resources of agency. The analysis discusses the utility of the AUS Scale for large-scale studies of student agency across countries.