Electronic information systems (EIS) are widely used in social work, but empirical research results about their use have yet to be disseminated and analysed. This scoping review of 36 articles published between 2000 and 2019 was conducted to summarise the existing body of knowledge to identify which themes have been the subject of previous research, as well as identifying gaps for future research. Four themes were identified: (1) the effects of using EISs on social work; (2) factors that have an impact on the use of EISs; (3) social workers’ strategies in the use of EISs and (4) the development of EISs with social workers. The findings show that the use of EISs changed the priorities of social work. However, social workers deviated from the rules of EISs to maintain their agency in relation to their work. The use of EISs’ lacked training, which led more to recording data instead of utilising it for professional purposes. Social workers’ participation in the development of EISs was seen essential to avoid unanticipated consequences. EISs are not limited to technical or usability challenges, but there are more profound issues that need further examination.